CVE REMEDIATION GUIDE
CISA KEV · Known exploitedCriticalResearch in progress

CVE-2025-20281 remediation guide

Cisco Identity Services Engine

A vulnerability in a specific API of Cisco ISE and Cisco ISE-PIC could allow an unauthenticated, remote attacker to execute arbitrary code on the underlying operating system as root. The attacker does not require any valid credentials to exploit this vulnerability. This vulnerability is due to insufficient validation of user-supplied input. An attacker could exploit this vulnerability by submitting a crafted API request. A successful exploit could allow the attacker to obtain root privileges on an affected device.

Open CVE record
Research in progress

A verified fixed-version field is not available. Use the linked NVD and supporting references, then confirm the vendor-supported path before changing production systems.

ProductCisco Identity Services Engine
Affected versions3.3.0, 3.3 Patch 2, 3.3 Patch 1, 3.3 Patch 3, 3.4.0, 3.3 Patch 4, 3.4 Patch 1, 3.3 Patch 5, 3.3 Patch 6
Fixed versionsNo verified fixed-version field is available yet
Priority basisImmediate · CVSS 10 · EPSS 97.1%
01

Identify the affected asset

Confirm whether Cisco Identity Services Engine is installed, record the deployed version and installation path, and identify exposed interfaces.

  • Record the product name, package or appliance identifier, and installed version.
  • Identify internet-facing, administrative, API, and internal access paths.
  • Preserve the pre-change configuration and relevant service logs.
02

Validate the affected-version match

Compare the deployed version with the affected range: 3.3.0, 3.3 Patch 2, 3.3 Patch 1, 3.3 Patch 3, 3.4.0, 3.3 Patch 4, 3.4 Patch 1, 3.3 Patch 5, 3.3 Patch 6. Treat incomplete inventory results as unresolved.

03

Prioritize with independent signals

CISA has listed this vulnerability in the Known Exploited Vulnerabilities catalog. Combine this signal with asset criticality, exposure, compensating controls, and business impact.

04

Apply supported remediation

Apply mitigations per vendor instructions, follow applicable BOD 22-01 guidance for cloud services, or discontinue use of the product if mitigations are unavailable.

05

Verify the result

Confirm the resulting version, service health, authentication and access paths, monitoring coverage, and relevant security logs.

  • Confirm the expected version and package state.
  • Run a functional health check for critical service paths.
  • Review authentication, error, application, and security monitoring logs.
  • Reassess exposure if the supported fix cannot be applied.

Operational boundary

This page does not replace the vendor advisory, support contract, change-management process, or recovery plan. Do not infer that an asset is unaffected from an incomplete inventory query or a missing fixed-version field.

CVE-2025-20281 Remediation Guide | SECUFOCUS NOW